GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs10461617 | 1 | rs11739344 | chr5:56111087 | C5orf35 | chr5:56205103-56213010:+ | 0.95 | 6.34 | 4.59E-8 | Type 2 diabetes |
| UVM | cis | rs11190604 | 1 | rs11816840 | chr10:102309220 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs78153629 | 1 | rs11858714 | chr15:40717447 | C15orf23 | chr15:40674922-40686488:+ | 0.91 | 5.13 | 3.95E-6 | Heschl's gyrus morphology |
| UVM | cis | rs10935120 | 1 | rs11919350 | chr3:134235970 | ANAPC13 | chr3:134196547-134204865:- | -0.46 | -6.87 | 6.1E-9 | Height |
| UVM | cis | rs10935120 | 1 | rs11927068 | chr3:134266321 | ANAPC13 | chr3:134196547-134204865:- | -0.46 | -6.87 | 6.1E-9 | Height |
| UVM | cis | rs10935120 | 1 | rs11928499 | chr3:134232350 | ANAPC13 | chr3:134196547-134204865:- | -0.46 | -6.48 | 2.65E-8 | Height |
| UVM | cis | rs11976020 | 1 | rs11976020 | chr7:72247800 | TYW1B | chr7:72023729-72298813:- | 1 | 9.04 | 1.85E-12 | Educational attainment (years of education) |
| UVM | cis | rs12049330 | 1 | rs12037569 | chr1:109923677 | RBM15 | chr1:110881945-110889303:+ | -0.49 | -4.9 | 8.84E-6 | Major depressive disorder |
| UVM | cis | rs11190604 | 1 | rs12219158 | chr10:102302923 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs12219789 | chr10:102213778 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs12237653 | 1 | rs12237653 | chr9:2551654 | FLJ35024 | chr9:2422702-2622373:- | 1.01 | 6.13 | 9.98E-8 | Gambling |
| UVM | cis | rs11190604 | 1 | rs12354411 | chr10:102294537 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs12355721 | chr10:102244911 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs12358187 | chr10:102284449 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs9527 | 1 | rs12416687 | chr10:104629011 | C10orf32 | chr10:104613967-104624718:+ | -0.37 | -4.66 | 2.03E-5 | Arsenic metabolism |